What we’ve seen so far.

6

Peer-reviewed publications

2

Animal species

Multiple

Disease models: Allergy, Autoimmune, Cancer and Transplant.

Published research has examined immune regulation, inflammatory activity, and defined treatment courses.

The signal has appeared more than once.

Across different models, the research has reported biological effects consistent with the AbstimX™ hypothesis.

Immune regulation

Inflammatory activity

Effects following defined treatment courses

Findings vary by study and model.

Naturally occurring disease.

AbstimX™ is currently being studied in dogs with naturally occurring allergic disease at an independent academic centre.

Clinical pilot underway.

Results are scheduled for 2027.

Animal evidence is not human proof.

That is the next question:

Animal models

Naturally occurring disease

Human translation

What remains unknown.

Human efficacy

Human durability

Comparative clinical benefit

AbstimX™ is investigational. Human efficacy has not been established.